Lymphocyte activation via receptor cross-linkage by macromolecules
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Lymphocyte activation via receptor cross-linkage by macromolecules molecular properties influencing activation and inhibition by haptenated polymers by Masako Okajima

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Published .
Written in English

Book details:

Edition Notes

Statementby Masako Okajima.
LC ClassificationsMicrofilm 88/7458 (R)
The Physical Object
Paginationxvi, 181 leaves
Number of Pages181
ID Numbers
Open LibraryOL1826953M
LC Control Number89894007

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clonal selection: The selection and activation by antigen of a lymphocyte bearing a complementary receptor, which then proliferates to form an expanded clone. clone: Identical cells derived from a single progenitor. colony‐stimulating factors (CSF): Factors that permit the proliferation and differentiation of hematopoietic cells. Connections between signal transduction components and cellular responses initiated by antigen receptor on B lymphocytes Article (PDF Available) in Journal of . Receptor Cross-Linkage Mediates B-Cell Activation B-cell activation in response to antigenic stimulation seems to follow one of two activation pathways; these alternatives may reflect the existence of two distinct types of antigenic substances. A study of cell traffic and activation in human allergen-induced LPRs in the skin revealed a lymphocyte infiltration that was almost ex- clusively CD4-positive (helper/inducer subset).'33 Some of these T cells were activated in that they stained positively for the presence of IL-2 Cited by:

Bruton’s tyrosine kinase (Btk) is a member of the Tec family kinases (TFKs), which form one of the largest kinase families in mammalians. TFK expression in different tissues plays an important role in a vast range of cellular signaling, and TFKs have been recognized as key players in B-cell antigen receptor (BCR) signaling. Within this family, the cytoplasmic Btk is mainly expressed in Cited by: 2. A lipid-modifying enzyme that, depending on the isoform, is activated upon activation of some G protein-coupled receptors (GPCRs) or of some receptor tyrosine kinases (RTKs). PLC cleaves phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) to release the second messengers inositol 1,4,5-triphosphate (IP3) into the cytosol and 1,2-diacylglycerol. receptor, the receptor-drug complex then moves to nucleus to modulate protein expression. USE: Prostate Cancer but contraindicated in breast and endometrial cancer AE: Increased risk of thromboembolism, migraine, cholestasis and mood changes - Gynecomastia & impotence when administered to men. A signal could be delivered directly through the receptors, either by an allosteric transition in the receptor itself or by cross-linkage or aggregation of receptor Ig in the fluid cell membrane.

Mast cells have been recognized for well over years. With time, human mast cells have been documented to originate from CD34 + cells, and have been implicated in host responses in both innate and acquired immunity. In clinical immunology, they are recognized for their central role in IgE-mediated degranulation and allergic inflammation by virtue of their expression of the high Cited by: Poster Abstracts | 7th Annual Peptide Therapeutics Symposium P18 Delivery of Macromolecules Using Fluorescent Cell-penetrating Peptides and Light: A Focus on Photo-endosomolysis Muthukrishnan, N. 32 ti 2 antigens activate b cells by extensively School No School; Course Title NONE 0; Type. Notes. Uploaded By MuneebA0. Pages 90 Ratings % (1) 1 out of 1 people found this document helpful; This preview shows page 32 - 43 out of 90 pages. Full text of "Goldman's Cecil Medicine, 24th Ed " See other formats.